Globulins Cohn fraction II, III 来源于山羊,5G,G5640-5G,Sigma

销售价: ¥ 2210.69 / 件
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订货号 : 0BT0641
品牌型号 : Sigma G5640-5G
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Vitamin D binding protein (DBP) is a polymorphic protein that specifically binds to vitamin D and its metabolites. This protein belongs to the albuminoid family and is highly conserved among vertebrates. The gene encoding DBP is mapped to human chromosome 4q11-q13. It is predominantly produced in the liver and is also expressed in the kidney, endocrine pancreatic cells, fat cells, and testis.


Application

Globulins were used in Biotin/avidin formulations.


Biochem/physiol Actions

Vitamin D binding protein (DBP) specifically binds and transports vitamin D and its metabolites with high affinity. It promotes fibrillar actin clearance by binding to actin monomers. DBP also binds to unsaturated fatty acids, megalin-cubilin receptor complex, the membrane of leukocytes, and the activation of the complement C5 system. The levels of DBP indicate the free concentration of all vitamin D metabolites. Decreased levels of serum DBP are observed in liver diseases, nephrotic syndrome, malnutrition, severe acute trauma, or disease.


Physical form

Lyophilized powder containing NaCl


Other Notes

Primarily γ-globulins


技术参数 Specifications
biological sourcegoat
Quality Segment300
assay73-90% protein basis (biuret)
formlyophilized powder
compositionProtein, 73-90% biuret
solubilityH2O: soluble 25 mg/mL
storage temp.2-8°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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