Anti-PD-L1/CD274 Antibody, clone 8F1V6, Rabbit Monoclonal，100UL，SAB5702238-100UL，Sigma

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订货号： 0BS9286

品牌型号： Sigma SAB5702238-100UL

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最小订货量： 1件

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商品介绍
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包装参数

产品介绍 Product Description

General description

Programmed death-ligand 1 (PD-L1) is a 40kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and non-hematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1-PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PD-L1 has become an important biomarker and immunotherapy target for many types of malignancies.

Immunogen

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Recombinant protein of human PD-L1/CD274.

Application

ELISA, WB, FC, Inhibition

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
material	colorless
clone	8F1V6, monoclonal
form	liquid
species reactivity	human
concentration	0.65 mg/mL
technique(s)	flow cytometry: 1:50 - 1:200
color	colorless
isotype	IgG
UniProt accession no.	Q9NZQ7
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... PD-L1(29126)

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