Monoclonal Anti-CD4L antibody produced in mouse，100UG，SAB3500124-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
Cluster of differentiation (CD4) encodes a T-cell surface glycoprotein CD4. In human chromosome, the gene CD4 is localized on 12p13.31.

Immunogen

raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.

Biochem/physiol Actions

Cluster of differentiation (CD4) mutation in single nucleotide causes OKT4 (Leu-3 T4) epitope deficiency. CD4 plays a major role in collateral artery formation by recruiting macrophages at the active site and through triggering the synthesis of arteriogenic cytokines.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	9H5A8, monoclonal
form	buffered aqueous solution
species reactivity	mouse, human, rat
technique(s)	immunohistochemistry: suitable,indirect ELISA: suitable,western blot: suitable
UniProt accession no.	P01730
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... CD4(920)

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