- 商品介绍
- 规格参数
- 包装参数
Immunogen
Synthetic peptide directed towards the N terminal region of human SIL1
Application
Anti-SIL1 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.
Biochem/physiol Actions
SIL1 nucleotide exchange factor is an N-linked glycoprotein present in the membrane of endoplasmic reticulum. In coordination with HSPA5, SIL1 regulates proper folding of newly synthesized of proteins and degrades proteins that fail to mature properly. SIL1 is also regulated by glucose and its activity is essential for glucose-stimulated insulin secretion by the pancreatic beta cells. Mutations in SIL1 cause cerebellar ataxia, chronic myopathy, cataracts, delayed motor development and intellectual disability, collectively known as Marinesco-Sjögren syndrome.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: KETKAEEELDAEVLEVFHPTHEWQALQPGQAVPAGSHVRLNLQTGEREAK
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 49 kDa |
| species reactivity | human, guinea pig, bovine, rabbit, rat, horse |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| web metadata keyword.default | 0.25µg/ml anti-SIL1 antibody for research,4-8µg/ml anti-SIL1 antibody immunohistochemical staining,anti-SIL1 antibody Sigma-Aldrich,anti-SIL1 antibody for protein detection,anti-SIL1 antibody for tissue section analysis,anti-SIL1 antibody immunohistochemistry paraffin-embedded tissue,anti-SIL1 antibody western blotting reagent,anti-SIL1 antibody with sodium azide and sucrose,anti-SIL1 antibody,anti-SIL1 homolog endoplasmic reticulum chaperone antibody,high-quality anti-SIL1 antibody for laboratory use,purified anti-SIL1 antibody 1x PBS buffer,rabbit anti-SIL1 antibody for western blotting,rabbit polyclonal anti-SIL1 antibody |
| NCBI accession no. | NP_071909 |
| UniProt accession no. | Q9H173 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... SIL1(64374) |
| 长度(mm) | |
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¥ 1082.93
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¥ 3317.36
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¥ 907.59
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¥ 1327.84
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¥ 314.94
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¥ 540.59
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¥ 46052.83
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