Monoclonal Anti-IL8 antibody produced in mouse,100UG,SAB1409244-100UG,Sigma

销售价: ¥ 4585.89 / 件
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订货号 0BS6127
品牌型号 Sigma SAB1409244-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. (provided by RefSeq)


Immunogen

IL8 (AAH13615, 21 a.a. ~ 99 a.a) full length recombinant protein.

Sequence
EGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS


Biochem/physiol Actions

Interleukin-8 (IL-8) chemoattracts and activates neutrophils. It is involved in guiding neutrophils and oligodendrocytes to sites of infection. The protein also stimulates angiogenesis and tumor growth. It is also associated with inflammatory diseases.


Physical form

Solution in phosphate buffered saline, pH 7.4


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1B4, monoclonal
formbuffered aqueous solution
mol wtantigen 8.69 kDa
species reactivityhuman
technique(s)immunoprecipitation (IP): suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.BC013615
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... IL8(3576)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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