- 商品介绍
- 规格参数
- 包装参数
General description
Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5′-[AG]TAAA[TC]A-3′. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3′UTR of MYC transcript and prevent its translation.
Immunogen
A synthesized peptide derived from human Phospho-FOXO3 (S253)
Physical form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preparation Note
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Other Notes
AV-pS-MD
| recombinant | expressed in HEK 293 F cells |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | 1E1, recombinant monoclonal |
| form | liquid |
| mol wt | 150 kDa |
| purified by | affinity chromatography |
| species reactivity | human |
| concentration | 0.8mg/ml |
| technique(s) | ELISA: 2000:10000,flow cytometry: 1:50-1:200,immunofluorescence: 1:50-1:200,immunohistochemistry: 1:50-1:200 |
| isotype | IgG |
| UniProt accession no. | O43524 |
| shipped in | wet ice |
| storage temp. | -10 to -25°C |
| target post-translational modification | phosphorylation (pSer253) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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¥ 1683.78
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¥ 2013.69
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¥ 5887.85
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¥ 1653.62
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¥ 1568.60
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¥ 1196.14
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¥ 2452.91
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¥ 3896.11
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¥ 2173.94
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