(R)-SKBG-1，25MG，SML3917-25MG，Sigma

Biochem/physiol Actions

Cell permeable high affinity ligand of RNA-binding protein NONO; stabilize NONO–RNA interactions and rapidly reduces the expression of transcripts encoding AR and AR variants.


(R)-SKBG-1 is a cell permeable high affinity ligand of RNA-binding protein NONO that binds to Cys 145 of NONO and stabilize NONO–RNA interactions. (R)-SKBG-1 rapidly and stereoselectively reduces the expression of transcripts encoding the androgen receptor (AR) and its splice variants in prostate cancer cells.