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Biochem/physiol Actions
Hexachlorophene is selective and potent N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor. Hexachlorophene potently inhibits NAPE-PLD activity in cultured HEK293 cells. Hexachlorophene is an antibacterial compound used topically by health-care personnel to control cutaneous gram-positive infections. Also it appears that hexachlorophene is an inhibitor of virus entry for Severe fever with thrombocytopenia syndrome virus (SFTSV).
Selective and potent N-acyl-phosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor; topical anti-bacterial agent
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | ClC1=C(C(O)=C(C=C1Cl)Cl)CC2=C(C(Cl)=CC(Cl)=C2O)Cl |
| InChI key | ACGUYXCXAPNIKK-UHFFFAOYSA-N |
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¥ 916.08
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¥ 1316.02
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¥ 520.54
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¥ 2005.84
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¥ 634.68
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¥ 911.06
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¥ 1790.42
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¥ 165230.53
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¥ 51018.02
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¥ 30616.15
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