Anti-Phospho-PPP1CA-T320 antibody produced in rabbit,100UL,SAB5700456-100UL,Sigma

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订货号 0BS2189
品牌型号 Sigma SAB5700456-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.


Immunogen

A phospho specific peptide corresponding to residues surrounding T320 of human PPP1CA


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 32, 37, 38
species reactivitymouse, human, rat
concentration2.36 mg/ml
technique(s)immunohistochemistry: 1:50-1:100,western blot: 1:500-1:2000
UniProt accession no.P62136
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pThr320)
Gene Informationhuman ... PPP1CA(5499)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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