- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Arglabin is a natural product with antitumor and anti-inflammatory activity. Arglabin competitively inhibits the binding of farnesyl diphosphate to farnesyl transferase (FTase), preventing the activation of RAS proto-oncogene by preventing the incorporation of farnesyl pyrophosphate into human H-ras proteins. Arglabin is also an inhibitor of the NLRP3 inflammasome. Arglabin reduces inflammation and plasma lipids and has shown a marked reduction in atherosclerotic lesions.
| biological source | semisynthetic (from parthenolide) |
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | protect from light |
| color | white to beige |
| storage temp. | −20°C |
| SMILES string | O1[C@@]32[C@@]1(CC[C@@H]4[C@H](OC(=O)C4=C)[C@@H]3C(=CC2)C)C |
| InChI | 1S/C15H18O3/c1-8-4-7-15-11(8)12-10(9(2)13(16)17-12)5-6-14(15,3)18-15/h4,10-12H,2,5-7H2,1,3H3/t10-,11-,12-,14-,15+/m0/s1 |
| InChI key | UVJYAKBJSGRTHA-ZCRGAIPPSA-N |
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¥ 2814.26
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¥ 1563.36
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¥ 2019.57
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¥ 9207.92
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¥ 2268.97
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¥ 5061.38
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