Anti-ANPRB/NRP2 Antibody, clone 1S1H1, Rabbit Monoclonal,100UL,SAB5702138-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BR7742
品牌型号 Sigma SAB5702138-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone1S1H1, monoclonal
formliquid
mol wt 130 kDa
species reactivityhuman, rat
concentration0.50 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceNLLLRMEQYANNLEKLVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAIIDNF
UniProt accession no.P20594
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ANPRB(4882)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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