- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Application
Tegaserod maleate has been used to study its cytotoxic effects on human astrocytes and to study its effects as an anti-glioblastoma agent.
Biochem/physiol Actions
It stimulates neurotransmitter release from enteric nerves and regularizes gastrointestinal function. Tegaserod has been used to treat irritable bowel syndrome associated with constipation and chronic constipation.
Tegaserod is a potent full agonist at serotonin 5-HT4 receptors with an EC50 of 7 nM.
Tegaserod is a serotonin 5-HT4 agonist.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N=C(NCCCCC)N/N=C/C1=CNC2=C1C=C(OC)C=C2.OC(/C=C\C(O)=O)=O |
| InChI | 1S/C16H23N5O.C4H4O4/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15;5-3(6)1-2-4(7)8/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21);1-2H,(H,5,6)(H,7,8)/b20-11+;2-1- |
| InChI key | CPDDZSSEAVLMRY-FEQFWAPWSA-N |
| Gene Information | human ... HTR4(3360) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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