Anti-Dystrophin antibody, Mouse monoclonal，100UL，SAB4200764-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Anti-Dystrophin antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from mouse immunized with fragment of recombinant human dystrophin. Dystrophin is a 427 kD protein which joins the actin cytoskeleton to laminin. It possesses multiple domains and is localized to the extracellular matrix. Dystrophin contains NH2-terminal domain for actin binding. The C-terminal domain interacts with dystrophin associated protein (DAP).
Dystrophin is a rod-shaped cytoskeletal protein located to the periphery (plasma membrane) of normal striated muscle fibers.

Immunogen

recombinant human dystrophin

Application

Anti-Dystrophin antibody, Mouse monoclonal has been used in immunoblotting and immunohistochemistry.

Biochem/physiol Actions

Anti-Dystrophin antibody, Mouse monoclonal specifically recognizes an epitope located on the rod domain of the human dystrophin molecule.
Dystrophin is known to prevent muscle fibre injury due to contraction.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

Other Notes

This product is for R&D use only, not for drug, household, or other uses.

技术参数 Specifications

biological source	mouse
Quality Segment	200
antibody form	purified from hybridoma cell culture
antibody product type	primary antibodies
clone	MANDYS8, monoclonal
form	buffered aqueous solution
mol wt	~427 kDa
species reactivity	porcine, rabbit, mouse, rat, human
enhanced validation	independent Learn more about Antibody Enhanced Validation
concentration	~1.0 mg/mL
technique(s)	immunoblotting: suitable,immunohistochemistry: 5-10 μg/mL using acetone fixed rat tongue frozen sections
isotype	IgG2b
UniProt accession no.	P11532
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... DMD(1756)

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