Anti-GSTM5 antibody produced in rabbit,100UG,SAB1410588-100UG,Sigma

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订货号 0BR1389
品牌型号 Sigma SAB1410588-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual′s susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. (provided by RefSeq)


Immunogen

GSTM5 (NP_000842.2, 1 a.a. ~ 218 a.a) full-length human protein.

Sequence
MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wtantigen 25.7 kDa
species reactivitymouse, human
technique(s)western blot: 1 μg/mL
NCBI accession no.NM_000851.2
UniProt accession no.P46439
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GSTM5(2949)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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