- 商品介绍
- 规格参数
- 包装参数
General description
Contains amino acids 29 to end with a C-terminal His tag, MW=89.1 kDa
Application
Dipeptidyl Peptidase VII (DPP7), also known as DPP2 or quiescent cell proline dipeptidase, is a post-proline cleaving aminopeptidase that is expressed in quiescent lymphocytes . DPP7 is used to study the regulation of cell quiescence . Like DPP4, DPP7 may be useful in diabetes and vascular disease research .
Biochem/physiol Actions
DPP7 is essential for maintaining lymphocytes and fibroblasts in G(0). The inhibition of DPP7 results in apoptosis, which is mediated by the induction of c-Myc and p53 . DPP7 has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.
Physical form
Supplied as a solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 220 mM imidazole, and 20% glycerol.
Other Notes
One unit will hydrolyze 1.0 picomole of Ala-Pro-AMC per minute at pH 7.4 at 25 deg °C
| recombinant | expressed in Sf9 cells |
| Quality Segment | 200 |
| form | solution |
| specific activity | ≥1,500 units/μg protein,≥1500 units/μg protein |
| mol wt | 89.1 kDa |
| relevant disease(s) | diabetes; cardiovascular diseases |
| shipped in | dry ice |
| storage temp. | −70°C |
| 长度(mm) | |
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| 重量(kg) |
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¥ 2528.88
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¥ 1779.22
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¥ 238.17
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¥ 3812.28
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¥ 4897.21
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¥ 2573.97
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¥ 2151.46
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¥ 2617.87
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¥ 1196.14
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