- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
WEB 2086 inhibits PAF mediated chemotaxis and leukotriene C4 production in eosinophils. It prevents surge in airway resistance and cardiovascular side effects mediated by PAF inhalation.
WEB2086 is a very potent, selective platelet-activating factor (PAF) antagonist (IC50 = 16 nM). WEB2086 inhibits the proliferation of tumor cells and slows tumor growth in xenograft tumor models, and has been shown to inhibit angiogenesis.
WEB2086 is a very potent, selective platelet-activating factor (PAF) antagonist.
Features and Benefits
This compound is featured on the PAF Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | DMSO: 10 mg/mL (clear solution) |
| storage temp. | 2-8°C |
| SMILES string | Cc1nnc2CN=C(c3ccccc3Cl)c4cc(CCC(=O)N5CCOCC5)sc4-n12 |
| InChI | 1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3 |
| InChI key | JGPJQFOROWSRRS-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 6894.69
-
询价
-
¥ 4390.38
-
¥ 1653.62
-
询价
-
¥ 1196.00
-
¥ 1783.21
-
¥ 5804.96
-
¥ 2288.54
-
¥ 5990.26
-
¥ 4614.63
-
¥ 56581.65
-
¥ 18741.69
-
询价
微信小程序
7X24小时在线咨询