Dilazep dihydrochloride,50MG,D5294-50MG,Sigma

销售价: ¥ 2940.07 / 件
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订货号 : 0BQ6965
品牌型号 : Sigma D5294-50MG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

Dilazep comprises central cyclic diamine and phenyl rings connected via alkyl linkers.


Application

Dilazep dihydrochloride has been used in estrogen receptor (ERα) antagonistic assay. It has also been used as an equilibrative nucleoside transporter inhibitor (ENT 1 and 2) in cancer cell lines.


Biochem/physiol Actions

Dilazep is a equilibrative nucleoside transporter 1 (ENTs) inhibitor. It is an antianginal drug and an effective coronary vasodilator. Dilazep elicits anti-albuminuric effects and is an anti-platelet agent. It is a potent adenosine uptake inhibitor and suppresses effects of ischemia.


技术参数 Specifications
formpowder
Quality Segment200
color white
solubilityH2O: 10 mg/mL
storage temp.2-8°C
SMILES stringCl[H].Cl[H].COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2
InChI1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H
InChI keyVILIWRRWAWKXRW-UHFFFAOYSA-N
Gene Informationhuman ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)
长度(mm)
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