- 商品介绍
- 规格参数
- 包装参数
General description
KCNA10 codes for a tetrameric protein that belongs to the potassium channel, voltage-gated (shaker-related) family. It is strongly expressed in hair cells of the inner ear in mice. A null mutation in Kcna10 has been linked to vestibular and hearing dysfunctions in mice.
Rabbit Anti-KCNA10 antibody recognizes human, mouse, rat, and chicken KCNA10.
Immunogen
Synthetic peptide directed towards the middle region of human KCNA10
Application
Rabbit Anti-KCNA10 antibody is suitable for western blot (1.25 μg/ml) and IHC (4-8 μg/ml) applications.
Biochem/physiol Actions
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Four sequence-related potassium channel genes, shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA10 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: PANVPIDIFADEISFYELGSEAMDQFREDEGFIKDPETLLPTNDIHRQFW
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 56 kDa |
| species reactivity | human, rat, mouse, bovine |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| web metadata keyword.default | KCNA10 antibody for inner ear research,KCNA10 antibody for vestibular dysfunction studies,anti-KCNA10 antibody for mouse studies,anti-KCNA10 antibody for protein channel analysis,anti-KCNA10 antibody for rat and chicken,anti-potassium voltage-gated channel KCNA10 antibody,high purity rabbit anti-KCNA10 antibody,immunohistochemistry KCNA10 antibody 4-8 µg/ml,purified rabbit anti-KCNA10 antibody 1x PBS,rabbit anti-KCNA10 antibody for neuroscience research,rabbit anti-KCNA10 antibody for research,rabbit anti-KCNA10 antibody,rabbit polyclonal anti-KCNA10 antibody,western blot KCNA10 antibody 1.25 µg/ml |
| NCBI accession no. | NP_005540 |
| UniProt accession no. | Q16322 |
| shipped in | wet ice |
| storage temp. | −20°C |
| Gene Information | human ... KCNA10(3744) |
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¥ 2290.21
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¥ 1573.49
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¥ 2068.25
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