KD-Validated Anti GRK2 Antibody, clone 23GB1515, Rabbit Monoclonal,1004G,SAB6012483-100UL,Sigma

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订货号 0BQ5857
品牌型号 Sigma SAB6012483-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer′s disease. [provided by RefSeq, Sep 2017]
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.


Immunogen

A synthesized peptide corresponding to a sequence within amino acids 650-689 of human GRK2 [NP_001610.2].


Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.


Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.


技术参数 Specifications
biological sourcerabbit (Monoclonal)
Quality Segment100
recombinantexpressed in HEK 293 cells
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clone 23GB1515, recombinant monoclonal
formbuffered aqueous glycerol solution
mol wt 80 kDa
species reactivityhuman, rat
packagingvial of 1.5 mL
enhanced validationrecombinant expression
Learn more about Antibody Enhanced Validation
sustainabilityGreener Alternative Product
concentration1 mg/ml
technique(s)flow cytometry: 1:2000,immunofluorescence: 1:100-:1000,western blot: 1:1,000-1:5,000
isotypeIgG
Ensembl | human accession no.ENSG00000173020
NCBI accession no.NP_001610.2
UniProt accession no.P25098
greener alternative categoryDfS-Developed
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GRK2(156)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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