MTSEA-Biotin-XX,10MG,SML4235-10MG,Sigma

销售价: ¥ 1747.08 / 件
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订货号 0BQ5826
品牌型号 Sigma SML4235-10MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

MTSEA biotin-XX is a membrane-impermeant crosslinker consisting of biotin-coupled 2-aminoethyl-methanethiosulfonate (MTSEA).


Application

MTSEA-Biotin-XX may be used to covalently label cysteine residues in proteins or thiol-containing molecules with a biotin tag for streptavidin-based detection, purification, or accessibility studies and, for biotinylation of 4TU‐labeled RNAs in direct RNA sequencing.


Biochem/physiol Actions

MTSEA-Biotin-XX selectively and efficiently labels cell surface thiols, including cysteine residues and specific RNA modifications (s4U and dm6A), forming disulfide bonds with enhanced reactivity. The extended -XX- linker facilitates optimal biotin-streptavidin interaction, while the overall structure allows for high-yield, rapid reactions. Biotin-XX-MTSEA enables imaging, purification, and sequencing applications through its ability to tag target molecules via methanethiosulfonate (MTS) reactions.


Disclaimer

Hygroscopic, Store with desiccant


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
storage conditiondesiccated
color white to beige
solubilityDMSO: 2 mg/mL, clear (warmed)
shipped inwet ice
storage temp.-10 to -25°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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