- 商品介绍
- 规格参数
- 包装参数
General description
Anti-ULK3 is produced in rabbit using as the immunogen a synthetic peptide corresponding to a fragment of human ULK3, conjugated to KLH. Unc-51-like kinase 3 (ULK3) belongs to the ULK family of serine/threonine kinases. ULK3 is an autophagy related protein with an N-terminal kinase domain, which shows high similarity to those of ULK1 and ULK2. ULK3 localizes to the elongating isolation membrane upon autophagy activation.
Application
Anti-ULK3 antibody produced in rabbit has been used in immunoblotting.
Biochem/physiol Actions
Unc-51-like kinase 3 (ULK3) controls abscission timing in response to lagging chromosomes. Overexpression of ULK3 induces autophagy and senescence. ULK3 is also a positive regulator of the Hedgehog signalling pathway.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen ~50 kDa |
| species reactivity | human |
| packaging | antibody small pack of 25 μL |
| concentration | ~1 mg/mL |
| technique(s) | western blot: 1-2 μg/mL using whole extracts of human U87 cells |
| UniProt accession no. | Q6PHR2 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ULK3(25989) |
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