- 商品介绍
- 规格参数
- 包装参数
Application
Acetylethylcholine mustard hydrochloride has been used as a precursor in ethylcholine aziridinium (AF64A) preparation. It has also been used in the pharmacokinetic study to investigate its role in neuromuscular junction (NMJ) signal transmission and function.
Biochem/physiol Actions
Acetylethylcholine mustard hydrochloride can reduce the contraction frequency of the myotubes by inhibiting the synthesis of acetylethylcholine (Ach) with the half-maximal inhibitory concentration (IC50) of 1.22 mM.
Acetylethylcholine mustard is a precursor for ethylcholine mustard aziridinium ion (AF-64A); irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.
Acetylethylcholine mustard is an irreversible ligand for the high affinity choline transport system; specific presynaptic long action cholinotoxin; inhibitor of choline acetyl-transferase.
Disclaimer
Extremely hygroscopic.
| Quality Segment | 100 |
| assay | >97% (GC) |
| form | powder |
| storage condition | desiccated |
| color | white |
| mp | 78-81 °C |
| solubility | H2O: >5 mg/mL,ethanol: soluble,methanol: soluble |
| storage temp. | −20°C |
| SMILES string | Cl[H].CCN(CCCl)CCOC(C)=O |
| InChI | 1S/C8H16ClNO2.ClH/c1-3-10(5-4-9)6-7-12-8(2)11;/h3-7H2,1-2H3;1H |
| InChI key | CHWPASAPXMNLKO-UHFFFAOYSA-N |
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¥ 1596.77
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¥ 2268.97
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¥ 2882.02
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¥ 2132.12
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¥ 954.17
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¥ 5804.96
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¥ 3662.39
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¥ 8072.66
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