Anti-phospho-PKC-pan (pThr⁴⁹⁷) antibody produced in rabbit,100UG,SAB4504099-100UG,Sigma

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订货号 0BQ4818
品牌型号 Sigma SAB4504099-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Protein kinase C is a member of the cAMP-dependent, cGMP-dependent, and protein kinase C (AGC) superfamily of protein kinases. It has more than14 isoforms. A catalytic domain with an ATP binding site and a substrate-binding site is found in all PKC isoforms.


Immunogen

The antiserum was produced against synthesized peptide derived from human PKC-pan around the phosphorylation site of Thr497.

Immunogen Range: 623-672


Application

Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit has been used in western blot analysis (1:500).


Biochem/physiol Actions

Protein kinase Cs (PKCs) are involved in the growth and function of the gastrointestinal tract and the immune response. PKCs regulates cyclins, cyclin-dependent kinases (cdks), cdk inhibitors, and cell division cycle 25 (cdc25) phosphatases.


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wtantigen 76 kDa
species reactivityrat, mouse, human
concentration~1 mg/mL
technique(s)ELISA: 1:40000,immunofluorescence: 1:100-1:500,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000
NCBI accession no.P05129,P05771,P17252,P24723,Q02156,Q04759,Q05513,Q05655
UniProt accession no.P24723
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pThr497)
Gene Informationhuman ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCQ(5588), PRKCZ(5590)
长度(mm)
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