Anti-RAS antibody produced in rabbit，100UL，SAB4301113-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Ras is a proto-oncogene and the gene encoding it is localized on human chromosome 11p15.5. It is a 21 kDa protein and is part of the small GTP-binding proteins superfamily.

Immunogen

Synthetic peptide corresponding to a region derived from 60-74 amino acids of Human v-Ha-ras Harvey rat sarcoma viral oncogene homolog

Biochem/physiol Actions

Ras is a guanine-nucleotide binding protein that couples tyrosine kinase receptor signals to mitogen activated protein (MAP) kinase cascade. It has an important role in cell growth. Ras is a substrate for farnesyltransferase (FTase) and when farnesylated, it is anchored to the membrane. Membrane localization of Ras is crucial for its cellular activity. Inhibition of Ras farnesylation is a target for anti-cancer drug development.
The antibody detects endogenous level of total RAS protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	21 kDa
species reactivity	mouse, rat, human
concentration	0.7 mg/mL
technique(s)	western blot: 1:200-1:1000 (Cell Lysate)
isotype	IgG
accession no.	NP_001123914.1
UniProt accession no.	P01112
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... HRAS(3265)

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