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General description
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
Immunogen
A synthetic phosphorylated peptide around T210 of human PLK1 (NP_005021.2).
Physical form
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Preparation Note
Store at -20℃. Avoid freeze / thaw cycles.
| biological source | rabbit |
| Quality Segment | 100 |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 68 |
| species reactivity | human |
| concentration | 2.04 mg/ml |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | P53350 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | phosphorylation (pThr204) |
| Gene Information | human ... PLK1(5347) |
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¥ 238.17
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¥ 2452.91
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¥ 4476.05
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¥ 5426.00
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¥ 15537.49
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¥ 51962.23
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¥ 402833.12
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