Monoclonal Anti-MXI1, (C-terminal) antibody produced in mouse,100UG,SAB1402279-100UG,Sigma

销售价: ¥ 4433.87 / 件
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订货号 0BQ1482
品牌型号 Sigma SAB1402279-100UG
货期 询货期
最小订货量 1件
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  • 商品介绍
  • 规格参数
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产品介绍 Product Description

General description

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. (provided by RefSeq)


Immunogen

MXI1 (NP_001008541.1, 73 a.a. ~ 182 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1F3, monoclonal
formbuffered aqueous solution
mol wtantigen ~38.21 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_001008541
UniProt accession no.P50539
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... MXI1(4601)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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