- 商品介绍
- 规格参数
- 包装参数
General description
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity.
Immunogen
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Human IgG
Application
WB, IHC
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 1U6H0, monoclonal |
| form | liquid |
| mol wt | 50 kDa |
| species reactivity | human |
| concentration | 0.23 mg/mL |
| technique(s) | immunohistochemistry: 1:50 - 1:300,western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| UniProt accession no. | P01857,P01859,P01860,P01861 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... IGHG1(3500) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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¥ 1148.92
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¥ 2013.69
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¥ 2019.57
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¥ 1779.22
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¥ 3275.78
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¥ 4897.21
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¥ 10277.12
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¥ 1196.00
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¥ 5061.38
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¥ 2869.87
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