Anti-RHOC antibody produced in rabbit,100UL,SAB5700030-100UL,Sigma

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订货号 0BP7549
品牌型号 Sigma SAB5700030-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RHOC (NP_001036144.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 22
species reactivityhuman, rat, mouse
concentration1.99 mg/ml
technique(s)immunofluorescence: 1:50-1:100,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:2000
UniProt accession no.P08134
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... RHOC(389)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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