- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
PA-6 (Pentamidine-Analogue 6) is a selective and potent IK1 (inward rectifier potassium current) inhibitor that terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. PA-6 interacts with the cytoplasmic pore region of the KIR2.1 (KCNJ2) ion channel.
selective and potent IK1 (inward rectifier potassium current) inhibitor that terminates atrial fibrillation
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| web metadata keyword.default | 1,5-Bis[4-[[imino(phenyl)methyl]amino]phenoxy]pentane chemical,KCNJ2 ion channel inhibitor PA-6,N,N′-[1,5-Pentanediylbis(oxy-4,1-phenylene)]bis-benzenecarboximidamide,PA-6 IK1 inhibitor,PA-6 Pentamidine-Analogue 6,PA-6 chemical structure and properties,PA-6 compound for pharmacological studies,PA-6 for cardiac research applications,PA-6 for veterinary cardiac studies,PA-6 inhibitor for ion channel research,PA-6 selective IK1 inhibitor for atrial fibrillation,Pentamidine-Analogue 6 atrial fibrillation treatment research,Pentamidine-Analogue 6 lab-grade,Sigma-Aldrich PA-6 500715-03-7,high-purity PA-6 for scientific research |
| storage temp. | 2-8°C |
| SMILES string | N=C(C1=CC=CC=C1)NC(C=C2)=CC=C2OCCCCCOC3=CC=C(NC(C4=CC=CC=C4)=N)C=C3 |
| InChI | 1S/C31H32N4O2/c32-30(24-10-4-1-5-11-24)34-26-14-18-28(19-15-26)36-22-8-3-9-23-37-29-20-16-27(17-21-29)35-31(33)25-12-6-2-7-13-25/h1-2,4-7,10-21H,3,8-9,22-23H2,(H2,32,34)(H2,33,35) |
| InChI key | PETGITKEGWIZEL-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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