Anti-ACSL4 Antibody, clone 4W3T9, Rabbit Monoclonal,100UL,SAB5702244-100UL,Sigma

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订货号 0BP3315
品牌型号 Sigma SAB5702244-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants.


Immunogen

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 42-321 of human ACSL4 (NP_075266.1).


Application

WB, IHC, IF/ICC, IP


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone4W3T9, monoclonal
formliquid
mol wt 79 kDa
species reactivityhuman, rat
concentration0.24 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,immunohistochemistry: 1:50 - 1:200,immunoprecipitation (IP): 1:500 - 1:1000,western blot: 1:10000 - 1:24000
color colorless
isotypeIgG
immunogen sequenceMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPL
UniProt accession no.O60488
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... FACL4(2182)
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