Monoclonal Anti-RFXAP antibody produced in mouse,100UG,SAB1402338-100UG,Sigma

销售价: ¥ 4046.38 / 件
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订货号 : 0BP3208
品牌型号 : Sigma SAB1402338-100UG
货期 : 询货期
最小订货量 : 1件
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  • 商品介绍
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产品介绍 Product Description

General description

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. (provided by RefSeq)


Immunogen

RFXAP (NP_000529, 179 a.a. ~ 244 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SDQALNCGGTASTGSAGNVKLEESADNILSIVKQRTGSFGDRPARPTLLEQVLNQKRLSLLRSPEV


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1B5, monoclonal
formbuffered aqueous solution
mol wtantigen ~33.37 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_000538
UniProt accession no.O00287
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... RFXAP(5994)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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