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Biochem/physiol Actions
SRS11-92 is a cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts. SRS11-92 protects against cell death in in a brain slice model of Huntington′s disease, an oligodendrocyte model of periventricular leukomalacia, and in isolated kidney proximal tubules model of kidney disfunction.
cell penetrant and potent inhibitor of ferroptosis that attenuates the cell death associated with frataxin knockdown in healthy human fibroblasts
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to yellow-brown |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N(C3CCCCC3)c1c(cc(cc1)C(=O)OCC)NCc2ccccc2 |
| InChI key | VHQAJFNLPQULSV-UHFFFAOYSA-N |
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