Anti-GFRA1 antibody produced in rabbit,100UL,SAB5700802-100UL,Sigma

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订货号 0BP1039
品牌型号 Sigma SAB5700802-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.


Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-280 of human GFRA1 (NP_665736.1).


Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.


Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt 50, 51
species reactivitymouse, human, rat
concentration1.37 mg/ml
technique(s)immunofluorescence: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P56159
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... GFRA1(2674)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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