- 商品介绍
- 规格参数
- 包装参数
General description
Immunoglobulins (Igs) or antibodies are Y-shaped molecules which are the secreted form of the B-cell receptor. Igs are composed of two heavy and two light chains. An immunoglobulin possesses variable (V) domains that bind to antigens and constant (C) domains that bind to effector molecules. Limited digestion using papain cleaves the antibody into three fragments, two of which are identical and contain the antigen-binding activity. They are known as fragment antigen binding (Fab) fragments. The third fragment does not possess antigen-binding activity and is known as fragment crystallizable (Fc). It interacts with cells and effector molecules. Pepsin cleaves the carboxy-terminal side of the disulfide bonds in the general region of the antibody and this gives rise to the F(ab′)2 fragment. The two antigen-binding arms of the antibody are linked in this fragment. There are five classes of immunoglobulins- IgM, IgA, IgG, IgD and IgE, classified based on their C regions.
Antibody format: IgG F(ab′)2
Immunogen
Mouse IgG IgA and IgM whole molecule
Biochem/physiol Actions
This product was prepared from monospecific antiserum by immunoaffinity chromatography using Mouse antigens coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities, pepsin digestion and chromatographic separation. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Alkaline Phosphatase and Anti-Goat Serum. No reaction was observed against Anti-Pepsin, Anti-Goat IgG F(c) or Human Serum Proteins. This reagent is suitable for the detection of all Mouse immunoglobulin subclasses and chain combinations.
Physical form
Supplied in 0.05 M Tris Chloride, 0.15M Sodium Chloride, 0.001M Magnesium Chloride, 0.0001M Zinc Chloride, 50% (v/v) Glycerol; pH 8.0 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Level | 100 |
| conjugate | alkaline phosphatase conjugate |
| antibody form | affinity isolated antibody |
| antibody product type | secondary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | mouse |
| concentration | 1.0 mg/mL |
| technique(s) | immunohistochemistry: suitable,indirect ELISA: suitable,western blot: suitable |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
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| 重量(kg) |
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¥ 1082.93
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¥ 916.08
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¥ 580.62
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¥ 3683.17
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¥ 968.94
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¥ 619.92
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¥ 852.85
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¥ 981.17
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¥ 1558.44
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¥ 3963.81
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