γ Secretase Inhibitor,5MG,SCP0004-5MG,Sigma

销售价: ¥ 2855.84 / 件
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订货号 0BN8217
品牌型号 Sigma SCP0004-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Gamma-secretase is a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. The leupeptin analogue Z-Leu-Leu-Nle-al (N-benzyloxycarbonyl-Leu-Leu-norleucinal; Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle)) and closely related peptides are used as protease and a gamma secretase inhibitors.


Application

γ Secretase Inhibitor has been used to study the suppressive miR-129 functions through inhibition on estrogen receptor 1 (ESR1) and NOTCH signaling in breast cancer stem cells.


技术参数 Specifications
assay≥95% (HPLC)
formlyophilized
compositionPeptide Content, ≥85%
storage conditionprotect from light
storage temp.−20°C
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