Anti-Phospho-VASP-S239 antibody produced in rabbit,100UL,SAB5701752-100UL,Sigma

销售价: ¥ 3692.64 / 件
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订货号 0BN8215
品牌型号 Sigma SAB5701752-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.


Immunogen

A phospho specific peptide corresponding to residues surrounding S239 of human Phospho-VASP-S239


Physical form

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivityhuman
concentration1.07 mg/mL
technique(s)immunohistochemistry: 1:50-1:100,western blot: 1:500-1:2000
UniProt accession no.P50552
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pSer239)
Gene Informationhuman ... VASP(7408)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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