Anti-phospho-Cyclin E1 (pThr³⁹⁵) antibody produced in rabbit,100UG,SAB4300684-100UG,Sigma

销售价: ¥ 5083.20 / 件
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订货号 0BN7972
品牌型号 Sigma SAB4300684-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.


Immunogen

Peptide sequence around phosphorylation site of threonine 395 (L-L-Tp-P-P), according to the protein NP_001229.1


Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
mol wt ~48 kDa
species reactivityhuman
concentration1 mg/mL
technique(s)western blot: 1:500-1:1000
isotypeIgG
immunogen sequence(L-L-Tp-P-P)
NCBI accession no.NM_001238.1
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pThr395)
Gene Informationhuman ... CCNE1(898)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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