- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
RSK4 is a member of the 90-kDa ribosomal S6 kinase family which are important components of growth factor mediated stimulation of cellular proliferation, survival and differentiation. RSK4 is activated via coordinated phosphorylation by ERK and 3-phosphoinositide-dependent protein kinase-1 (PDK1). RSK4 is often associated with contiguous gene syndromes consisting of X-linked deafness type 3 (DFN3), mental retardation (MRX) and choroideremia (CHM). RSK4 is most abundantly expressed in the brain and kidney.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Level | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 459-621 nmol/min·mg |
| mol wt | ~112 kDa |
| UniProt accession no. | Q9UK32 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... RPS6KA6(27330) |
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| 重量(kg) |
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