INSL5/INSL7 HYBRID human，25UG，SRP3304-25UG，Sigma

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订货号： 0BN6042

品牌型号： Sigma SRP3304-25UG

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最小订货量： 1件

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商品介绍
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产品介绍 Product Description

Biochem/physiol Actions

The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.7 kDa protein consisting of a 27 amino acid B-chain disulfide linked to a 21 amino acid A-chain.

Physical form

Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

技术参数 Specifications

biological source	human
recombinant	expressed in E. coli
assay	≥98% (HPLC),≥98% (SDS-PAGE)
form	lyophilized
mol wt	5.7 kDa
packaging	pkg of 25 μg
impurities	<0.1 EU/μg endotoxin, tested
color	white to off-white
UniProt accession no.	Q9Y5Q6 / Q8WXF3
shipped in	wet ice
storage temp.	−20°C
Gene Information	human ... INSL5(10022), RLN3(117579)

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