- 商品介绍
- 规格参数
- 包装参数
General description
Gadobutrol is a highly water-soluble, macrocyclic, and electrically neutral gadolinium-based contrast agent (GBCA) used in contrast-enhanced MRI. Its active component is a non-ionic, paramagnetic complex of gadolinium (Gd3+) chelated with butrol, forming the distinct gadobutrol structure. Gadobutrol exhibits the greatest shortening of proton T1 relaxation times amongst all macrocyclic GBCAs, a key determinant of signal and contrast enhancement in MRI.
Application
Gadobutrol may be used to enhance diagnostic contrast in magnetic resonance imaging (MRI) of pathological lesions in the liver, central nervous system (CNS), kidney, and brain.
Biochem/physiol Actions
Water-soluble macrocyclic gadolinium-based MRI contrast agent excreted renally, enhances CNS pathology detection by improving blood-brain barrier visualization.
Upon intravenous administration, it enhances MRI sensitivity for detecting CNS pathologies associated with blood-brain barrier defects, areas of altered perfusion, or expanded extracellular space. This agent is particularly effective in visualizing tumors, inflammatory processes, and demyelinating diseases of the CNS. Gadobutrol is eliminated unchanged via the kidneys, with negligible extra-renal excretion.
| Quality Level | 100 |
| assay | ≥95% (Gadolinium, elemental analysis) |
| form | powder |
| color | white to beige |
| solubility | H2O: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | OC[C@H](N1CCN(CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)CC([O-])=O)[C@@H](O)CO.[Gd+3] |
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¥ 1125.70
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¥ 805.47
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¥ 827.30
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¥ 2355.14
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¥ 1260.99
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 1142.57
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¥ 1334.26
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¥ 1604.79
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¥ 981.17
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¥ 381.67
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¥ 2170.40
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