帕罗西汀马来酸盐，10MG，P1372-10MG，Sigma

销售价： ¥ 1618.53 / 件

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订货号： 0BN1363

品牌型号： Sigma P1372-10MG

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最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

Biochem/physiol Actions

Paroxetine is a strong cytochrome P450 2D6 isotype (CYP2D6) inhibitor, which reduces the effectiveness of tamoxifen. This phenylpiperidine derivative inhibits clozapine metabolism. Paroxetine is used to treat social phobia, obsessive-compulsive disorder and panic disorder. It is also used to treat the premenstrual dysphoric disorder, post-traumatic stress disorder and chronic headache.
Paroxetine maleate is a selective serotonin reuptake inhibitor; antidepressant.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold with the permission of GlaxoSmithKline

技术参数 Specifications

Quality Level	100
assay	≥98% (HPLC)
form	solid
color	white to off-white
solubility	DMSO: ~12 mg/mL,H₂O: insoluble
originator	GlaxoSmithKline
storage temp.	2-8°C
SMILES string	OC(=O)\C=C/C(O)=O.Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3
InChI	1S/C19H20FNO3.C4H4O4/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;5-3(6)1-2-4(7)8/h1-6,9,14,17,21H,7-8,10-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,17-;/m0./s1
InChI key	AEIUZSKXSWGSRU-QXGDPHCHSA-N
Gene Information	human ... SLC6A4(6532)