- 商品介绍
- 规格参数
- 包装参数
General description
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Immunogen
Purified CD271 protein isolated from human melanoma cell line A875
Biochem/physiol Actions
The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.
Physical form
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Preparation Note
Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.
Other Notes
The antibody solution should be gently mixed before use.
| conjugate | unconjugated |
| Quality Level | 100 |
| antibody product type | primary antibodies |
| clone | NGFR5, monoclonal |
| form | buffered aqueous solution |
| species reactivity | human, ( Non-human primates), ( Rabbit), ( Cat) |
| concentration | 1 mg/ml |
| technique(s) | flow cytometry: suitable,immunocytochemistry: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable |
| isotype | IgG1 |
| UniProt accession no. | P08138 |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... NGFR(4804) |
| 长度(mm) | |
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询价
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¥ 521.16
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¥ 1987.51
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¥ 1137.02
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¥ 1047.15
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¥ 968.94
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¥ 1147.95
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¥ 634.68
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¥ 962.68
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¥ 17652.29
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¥ 51962.23
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