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- 规格参数
- 包装参数
Biochem/physiol Actions
Orally available neurogenic drug that ameliorates impaired memory function in Zucker diabetic fatty rats; exhibits long-acting antidepressant, procognitive, synaptoplastic, and neurotrophic activities.
NSI-189 is an orally available neurogenic drug with pleiotropic properties that ameliorates impaired memory function and plasticity in Zucker diabetic fatty rat model of type 2 diabetes through enhanced expression of mitochondrial complexes I, III, IV, and V. NSI-189 exhibits long-acting antidepressant, procognitive, synaptoplastic, and neurotrophic activities in patients with major depressive disorder.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | N2(CCN(CC2)C(=O)c3c(nccc3)NCCC(C)C)Cc1ccccc1 |
| InChI | 1S/C22H30N4O/c1-18(2)10-12-24-21-20(9-6-11-23-21)22(27)26-15-13-25(14-16-26)17-19-7-4-3-5-8-19/h3-9,11,18H,10,12-17H2,1-2H3,(H,23,24) |
| InChI key | DYTOQURYRYYNOR-UHFFFAOYSA-N |
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¥ 1596.77
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¥ 2290.21
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¥ 2013.69
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¥ 8293.41
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