Anti-phospho-ETS1 (pThr³⁸) antibody produced in rabbit，100UG，SAB4503912-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

ETS1 (E26 transformation specific sequence 1) is a proto‐oncogene. It is a member of the family of ETS transcriptional factors. ETS1 is usually expressed in lymphoid cells. This gene is mapped to human chromosome 11q24.

Immunogen

The antiserum was produced against synthesized peptide derived from human ETS1 around the phosphorylation site of Thr38.

Immunogen Range: 11-60

Biochem/physiol Actions

ETS1 (E26 transformation specific sequence 1) participates in Pol ι‐mediated progression of ESCC (esophageal squamous cell carcinoma). This gene controls cancer cell invasion, metastasis and EMT (epithelial to mesenchymal transition). ETS1 also plays important roles in the lymphocyte development, function, apoptosis and inflammation.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	antigen 50 kDa
species reactivity	rat, human, mouse
concentration	~1 mg/mL
technique(s)	ELISA: 1:10000,immunofluorescence: 1:100-1:500,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000
NCBI accession no.	P14921
UniProt accession no.	P14921
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	phosphorylation (pThr38)
Gene Information	human ... ETS1(2113)

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