- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
LY2033298 is a positive allosteric modulator of muscarinic M4 receptor.
LY2033298 is a robust allosteric potentiator that is highly selective for the human M4 muscarinic acetylcholine receptor subtype. LY2033298 potentiates ACh-M4 binding, with no effect at M1/3/5 receptors. LY2033298 can also bind to the M ACh receptor, and mediate either positive or negative allosteric effects depending on the ligand used to probe receptor activity.
Features and Benefits
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| storage condition | desiccated |
| color | off-white to tan |
| solubility | DMSO: >20 mg/mL |
| originator | Eli Lilly |
| storage temp. | −20°C |
| SMILES string | COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl |
| InChI | 1S/C13H14ClN3O2S/c1-5-7-9(15)10(11(18)16-6-3-4-6)20-13(7)17-12(19-2)8(5)14/h6H,3-4,15H2,1-2H3,(H,16,18) |
| InChI key | CTEGQKDJTBWFHW-UHFFFAOYSA-N |
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¥ 8520.40
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