Anti-NXF1 antibody produced in rabbit,100UL,SAB5701452-100UL,Sigma

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订货号 0BM6959
品牌型号 Sigma SAB5701452-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]


Immunogen

A synthesized peptide derived from human NXF1


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, rat, mouse
concentration0.14 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.Q9UBU9
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... NXF1(10482)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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