Anti-Integrin alpha V (ITGAV/CD51) Antibody, clone 10T9N2, Rabbit Monoclonal,100UL,SAB5702151-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BM5261
品牌型号 Sigma SAB5702151-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 949-1048 of human Integrin alpha V (ITGAV/CD51) (NP_002201.2).
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IHC, FC


技术参数 Specifications
biological sourcerabbit
Quality Level100
materialcolorless
clone10T9N2, monoclonal
formliquid
mol wt 140 kDa
species reactivityhuman, rat
concentration1 mg/mL
technique(s)flow cytometry: 1:50 - 1:200,immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
UniProt accession no.P06756
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ITGAV(3685)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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