Anti-HDAC4 Antibody, clone 9A6E2, Rabbit Monoclonal,100UL,SAB5702062-100UL,Sigma

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订货号 0BM1817
品牌型号 Sigma SAB5702062-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HDAC4 (P56524).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
materialcolorless
clone9A6E2, monoclonal
formliquid
mol wt 140 kDa
species reactivityhuman
concentration0.39 mg/mL
technique(s)western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQL
UniProt accession no.P56524
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... HDAC4(9759)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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