- 商品介绍
- 规格参数
- 包装参数
General description
Histones make up the nucleosome, which is the fundamental unit of the chromatin. Each nucleosome consists of 146 base pairs of DNA which is wrapped around an octamer of four core histones H2A, H2B, H3 and H4. Histone cluster 2 H2A family member c (HIST2H2AC) has many variants. Human Histone 2A (GenBank Accession No. NM_033445) amino acids 2-130 (end) with N-terminal His-tag, MW = 14.8 kDa, expressed in an E. coli expression system.
Histone cluster 2 H2A family member c (HIST2H2AC) is located on human chromosome 1q21. It is usually present in undifferentiated/proliferating cells. This canonical histone isoform has a protruding tail at both the N- and C-termini.
Biochem/physiol Actions
Histone cluster 2 H2A family member c (HIST2H2AC) has a role in maintaining the structure of the chromatin.
Histone cluster 2 H2A family member c (HIST2H2AC) participates in multiple epigenetic regulations and carcinogenesis. It also participates in embryonic stem (ES) cell biology and regulates the expression of genes. It modulates proliferation and epithelial-mesenchymal transition in mammary epithelial and breast cancer cells. Hist2h2ac also controls epithelial differentiation.
| biological source | human |
| recombinant | expressed in E. coli |
| assay | ≥90% (SDS-PAGE) |
| form | aqueous solution |
| mol wt | 14.8 kDa |
| packaging | pkg of 1 mg |
| storage condition | avoid repeated freeze/thaw cycles |
| concentration | 1.2 mg/mL |
| NCBI accession no. | NM_033445 |
| UniProt accession no. | Q16777 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... HIST2H2AC(8338) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 2013.69
-
¥ 2019.57
-
¥ 4039.86
-
询价
-
询价
-
询价
-
询价
-
¥ 3275.78
-
询价
-
询价
-
询价
-
询价
-
¥ 5725.45
-
询价
-
¥ 10277.12
-
无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
-
¥ 4404.38
-
询价
-
¥ 3896.11
微信小程序
7X24小时在线咨询