ᴅ-葡萄糖-6-磷酸 二钠盐 水合物,5G,10127647001,Roche

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订货号 0BM1461
品牌型号 Roche 10127647001
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Disodium salt


Application

Substrate for glucose-6-phosphatase.


Biochem/physiol Actions

In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.


Preparation Note

77% glucose-6-P (enzymatic), 13% sodium, 8% water
C6H11O9PNa2


Analysis Note

Contaminants: <0.2% glucose (enzymatic)


Other Notes

仅用于生命科学研究。不可用于诊断。


技术参数 Specifications
formsolid
mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
packagingpkg of 5 g
manufacturer/tradenameRoche
shipped inambient
SMILES stringO.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
InChI1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
InChI keyUUWJZXLTPORJKW-WYFATIGWSA-L
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